[Prenosologic criteria of health disorders and cardiovascular risk factors in workers engaged into nuclear industry].

Prophylactic study among workers engaged into main production of Siberian chemical enterprise (Seversk city) revealed high frequency of cardiovascular risk factors (overweight, hypodynamia, dyslipidemia, arterial hypertension), low level of adaptational potential and integral somatic health parameter as prenosologic criteria of cardiovascular diseases. The results necessitate recommendations to supplement periodic medical examinations with studies aimed to reveal early criteria of health disorders, and determine priority directions to specify prophylactic measures in nuclear industry workers.

[The prospects for the further development of the Belokurikha spa and health resort territory in the Altai Krai (region)].

We undertook a balneological survey of the Belokurikha spa and health resort territory with the purpose of distinguishing and identifying the potential health-improvement areas most promising for the extension and optimization of the therapeutic, tourist and recreational activities. The assessment was focused on the characteristic of the landscape and climatic conditions of the territory, the possibilities for the development of the existing resources of mineral waters and therapeutic muds as well as for the discovery of the potential new ones. The recommendations are proposed to promote the development of different forms of tourism with special reference to its medical and health-improvement aspects. It is suggested that the territory of the «Belokurikha¼ resort¼, «Belokurikha-2¼ and «Belokurikha-3¼ health-improvement areas should be integrated into a single spa-and-health resort district of federal importance.

[Evaluation of immunological responsiveness in female students during an academic year]. / Otsenka immunologicheskoi reaktivnosti u studentok v techenie uchebnogo goda.

Examining 17 untrained female students and 110 trained ones indicated that moderate exercises as aerobic ones did not exert a great impact on most parameters of cellular and humoral immunity. Exclusions were higher absolute counts of B lymphocytes in the trained students than those in the untrained ones at the end of an academic year (in spring). Despite their activity, all the female students were found to have seasonal variations in some immunological parameters. Among other things, the content of immunoglobulins (primarily classes G and A) dropped in winter and particularly in spring as compared to autumn; on the contrary, the parameters of phagocytosis significantly increased in winter versus autumn, then fell in spring months as compared to winter; vive versa, the count of circulating immune complexes substantially reduced in winter as compared with autumn, then showing a trend for an increase in spring, at the end of an academic year.

[Auditory and verbal agnosia in the left-handed patient: comparison of neuropsychological data, magnetic resonance and positron emission tomography]. / Slukhorechevaia agnoziia u levshi: sopostavlenie dannykh neiropsikhologicheskogo analiza, magnitno-resonansnoi i pozitronno- émissionnoi tomografii.

A case of the post-traumatic auditory-and-speech agnosia in a left-handed female patient is presented. The patient (a professional painter) showed satisfactory recovery in painting, speech production, reading and writing, whereas a severe deficit in auditory recognition of speech, melodies and rhythms persisted over time. She was also impaired in some aspects of visual recognition including prosopagnosia. To study this patient comprehensively, a neuropsychological assessment was combined with structural (magnetic resonance imaging-MRI) and metabolic (positron emission tomography--PET) data. Both PET and MRI revealed a large bilateral cortical damage in the medial basal cortex of the frontal, temporal and occipital lobes along with the anterior half of the lateral temporal cortex. In the left hemisphere the damaged area involved the whole temporal lobe, a large part of the occipital lobe and the opercular frontal and parietal regions. The relationship of the symptoms with the brain damage extension is discussed taking into account the left-handedness of the patient.

[Joint PET and electrophysiological research on human thinking activity]. / Sovmestnye PET i élektrofiziologicheskie issledovaniia myslitel'noi deiatel'nosti cheloveka.

Recent studies of a group of researchers from the Institute of Human Brain (St.-Petersburg), concerning the role of the distributed brain systems in different kinds of perceptual and cognitive acts, are reviewed in this paper. Principally different approaches were used, i. e., electrophysiological (multi-unit record with implanted electrodes) and positron emission tomography (PET). Possibility and benefit of application of the combined analysis of these different sets of data in order to obtain more detailed information on the work of the brain systems are discussed. On the basis of some examples of such a combined analysis the authors conclude that such a combined approach is the optimal way to reach a deeper insight into the anatomical-functional organization of the human brain.

[Changes in the content of iron, copper and manganese in animals during disadaptation caused by heavy loads]. / Izmenenie soderzhaniia zheleza, medi i margantsa v organizme zhivotnykh pri dizadaptatsii, vyzvannoi vozdeistviem bol'shikh nagruzok.

The exchange of microelements in the animal organisms under the influence of overtraining with static loads has been studied. In chronic experiments on 11 male dogs of impure-breed by the method of emission spectral analysis it has been established that the heavy physical loads cause the decrease of iron content in blood and a simultaneous reduction of the iron content and, partially, copper and manganese content in the internal organs of animals. The addition of microelements to the usual food allowance promotes the faster restoring of the violated microelement balance and animals' capacity for work.

[Zinc and silicon metabolism in highly trained athletes during heavy exercise]. / Obmen tsinka i kremniia u sportsmenov vysokoi kvalifikatsii pri bol'shikh sportivnykh nagruzkakh.

Trained male athletes were under study. It was found that under the effect of physical stress during the contest in ski race (30 and 50 km) the increase of the zink and silicon levels in the blood plasma correlated with their decrease in the blood cells. A positive zink and silicon equilibrium was observed in the athletes on the day of rest before the contest. Excretion of zinc and especially of silicon through the kidneys and intestine drastically grew on the day of the contest. On the day of rest following the high muscular stress the loss of trace elements appreciably lowered, however, it was higher than that before the contest. The authors recommend the following doses of the trace elements for highly trained athletes: zink--20-25 mg/day, silicon--30-35 mg/day.

[Effect of alcohol on iron, aluminum and zinc balance]. / Izmenenie balansa zheleza, aliuminiia i tsinka pod vliianiem alkogolia.

An increased loss of iron, aluminium and zinc through the intestine and kidneys, creating the preconditions for the development of deficiency of these metals in the body, was recorded in males and females, engaged in sports, after single intake of moderate doses of alcohol. The next day after the alcohol intake males showed elevated retention of iron, aluminium and zinc, while females--that of iron only. In the latter the loss of aluminium and zinc still prevailed over intake of these metals with food.